Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [49-170]' and Ligand = 'BDBM363500'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM363500 (9-(3,5-Dimethylisoxazol-4-yl)-6-methoxy-3-pyridin-...) Show SMILES COc1nn2C(COc3c(ccc1c23)-c1c(C)noc1C)c1ccccn1 |(3.4,12.23,;3.8,10.74,;2.71,9.65,;.04,9.65,;.04,8.11,;-1.29,7.34,;-1.29,5.8,;.04,5.03,;1.38,5.8,;2.71,5.03,;4.04,5.8,;4.04,7.34,;2.71,8.11,;1.38,7.34,;2.71,3.49,;1.47,2.58,;.13,3.35,;1.94,1.12,;3.48,1.12,;3.96,2.58,;5.29,3.35,;-2.62,8.11,;-2.62,9.65,;-3.96,10.42,;-5.29,9.65,;-5.29,8.11,;-3.96,7.34,)| Show InChI InChI=1S/C20H18N4O3/c1-11-17(12(2)27-23-11)13-7-8-14-18-19(13)26-10-16(15-6-4-5-9-21-15)24(18)22-20(14)25-3/h4-9,16H,10H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<200	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation; Incyte Holdings Corporation US Patent					Assay Description BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...				US Patent US9850257 (2017) BindingDB Entry DOI: 10.7270/Q2CF9SDT
					More data for this Ligand-Target Pair