Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [49-170]' and Ligand = 'BDBM363503'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM363503 (US9850257, Example 10) Show SMILES Cc1noc(C)c1-c1ccc2c3c1OCC(c1cccnc1)n3[nH]c2=O |(.13,-2.57,;1.47,-3.34,;1.94,-4.81,;3.48,-4.81,;3.96,-3.34,;5.29,-2.57,;2.71,-2.44,;2.71,-.9,;4.04,-.13,;4.04,1.41,;2.71,2.18,;1.38,1.41,;1.38,-.13,;.04,-.9,;-1.29,-.13,;-1.29,1.41,;-2.62,2.18,;-2.62,3.72,;-3.96,4.49,;-5.29,3.72,;-5.29,2.18,;-3.96,1.41,;.04,2.18,;.04,3.72,;2.71,3.72,;3.8,4.81,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation; Incyte Holdings Corporation US Patent					Assay Description BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 20 μL for BD1 and 40 μL for BD2. Inhib...				US Patent US9850257 (2017) BindingDB Entry DOI: 10.7270/Q2CF9SDT
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