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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [49-170]' and Ligand = 'BDBM480526'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [49-170]


(Homo sapiens (Human))		BDBM480526
PNG
(3-Cyclopropyl-1-(3-(difluoromethyl)-2-(tetrahydro-...)
Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2nc(C3CCOCC3)c(cc12)C(F)F
Show InChI InChI=1S/C26H28F2N4O2/c1-14-26(33)31(2)13-21-23(30-25(32(14)21)16-6-7-16)17-4-3-5-20-18(17)12-19(24(27)28)22(29-20)15-8-10-34-11-9-15/h3-5,12,14-16,24H,6-11,13H2,1-2H3
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...

US Patent US10899769 (2021)


BindingDB Entry DOI: 10.7270/Q2H41VJJ
More data for this
Ligand-Target Pair