Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [49-170]' and Ligand = 'BDBM480572'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480572 (5-(3-cyclopropyl-5,7- dimethyl-6-oxo-5,6,7,8- tetr...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C#N Show InChI InChI=1S/C25H23N7O/c1-14-25(33)30(2)13-21-23(29-24(32(14)21)15-7-8-15)18-5-4-6-20-19(18)9-16(10-26)22(28-20)17-11-27-31(3)12-17/h4-6,9,11-12,14-15H,7-8,13H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480572 (5-(3-cyclopropyl-5,7- dimethyl-6-oxo-5,6,7,8- tetr...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2nc(-c3cnn(C)c3)c(cc12)C#N Show InChI InChI=1S/C25H23N7O/c1-14-25(33)30(2)13-21-23(29-24(32(14)21)15-7-8-15)18-5-4-6-20-19(18)9-16(10-26)22(28-20)17-11-27-31(3)12-17/h4-6,9,11-12,14-15H,7-8,13H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	424	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair