BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [49-170]' and Ligand = 'BDBM480580'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [49-170]


(Homo sapiens (Human))		BDBM480580
PNG
(3-cyclopropyl-1-(3-(1,3- dimethyl-1H-pyrazol-4- yl...)
Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2cc(ncc12)-c1cn(C)nc1C
Show InChI InChI=1S/C25H26N6O/c1-14-20(12-30(4)28-14)21-10-17-6-5-7-18(19(17)11-26-21)23-22-13-29(3)25(32)15(2)31(22)24(27-23)16-8-9-16/h5-7,10-12,15-16H,8-9,13H2,1-4H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...

US Patent US10899769 (2021)


BindingDB Entry DOI: 10.7270/Q2H41VJJ
More data for this
Ligand-Target Pair