Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [49-170]' and Ligand = 'BDBM480603'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480603 (5,7-dimethyl-1-(3-(1- methyl-1H-pyrazol-3- yl)isoq...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2cc(ncc12)-c1ccn(C)n1 Show InChI InChI=1S/C26H28N6O2/c1-16-26(33)30(2)15-23-24(28-25(32(16)23)17-8-11-34-12-9-17)19-6-4-5-18-13-22(27-14-20(18)19)21-7-10-31(3)29-21/h4-7,10,13-14,16-17H,8-9,11-12,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [49-170] (Homo sapiens (Human))	BDBM480603 (5,7-dimethyl-1-(3-(1- methyl-1H-pyrazol-3- yl)isoq...) Show SMILES CC1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2cc(ncc12)-c1ccn(C)n1 Show InChI InChI=1S/C26H28N6O2/c1-16-26(33)30(2)15-23-24(28-25(32(16)23)17-8-11-34-12-9-17)19-6-4-5-18-13-22(27-14-20(18)19)21-7-10-31(3)29-21/h4-7,10,13-14,16-17H,8-9,11-12,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System US Patent					Assay Description BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...				US Patent US10899769 (2021) BindingDB Entry DOI: 10.7270/Q2H41VJJ
					More data for this Ligand-Target Pair