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Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [75-147]' and Ligand = 'BDBM313806'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4 [75-147]


(Homo sapiens (Human))		BDBM313806
PNG
(US10167292, Example 50)
Show SMILES Cc1nnn2CCN(c3ccc(Cl)cc3)c3cc(ccc3-c12)C(O)C(F)(F)F
Show InChI InChI=1S/C19H16ClF3N4O/c1-11-17-15-7-2-12(18(28)19(21,22)23)10-16(15)26(8-9-27(17)25-24-11)14-5-3-13(20)4-6-14/h2-7,10,18,28H,8-9H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Catalyst Therapeutics Pty Ltd.

US Patent


Assay Description
BRD binding and inhibition was assessed by measuring the interaction of biotinylated acetyl-histone H4 peptide (Anaspec #64989) with the BRD target p...

US Patent US10167292 (2019)


BindingDB Entry DOI: 10.7270/Q2765HFS
More data for this
Ligand-Target Pair