Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-1-tetrahydrofolate synthase, cytoplasmic' and Ligand = 'BDBM50580122'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-1-tetrahydrofolate synthase, cytoplasmic (Homo sapiens)	BDBM50580122 (CHEMBL5074925) Show SMILES Cn1c2ccc(cc2c(=O)n(Cc2ccc(Cl)c(Cl)c2)c1=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of C-terminal His-tagged human MTHFD1 (1 to 306 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for 1...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00663 BindingDB Entry DOI: 10.7270/Q2B56PKM
					More data for this Ligand-Target Pair