Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 1' and Ligand = 'BDBM50518092'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50518092 (CHEMBL4439854) Show SMILES OC1=C(C(N(C1=O)c1ccc(Br)cc1F)c1cccc(Br)c1)C(=O)C1CC1 |t:1| Show InChI InChI=1S/C20H14Br2FNO3/c21-12-3-1-2-11(8-12)17-16(18(25)10-4-5-10)19(26)20(27)24(17)15-7-6-13(22)9-14(15)23/h1-3,6-10,17,26H,4-5H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]-CCR2-RA-[R] from human TEV protease site linked CCR1 expressed in human U20S cell membranes co-expressing Gal4-VP16 transcriptio...				J Med Chem 61: 9146-9161 (2018) Article DOI: 10.1021/acs.jmedchem.8b00605 BindingDB Entry DOI: 10.7270/Q2222Z5H
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50518092 (CHEMBL4439854) Show SMILES OC1=C(C(N(C1=O)c1ccc(Br)cc1F)c1cccc(Br)c1)C(=O)C1CC1 |t:1| Show InChI InChI=1S/C20H14Br2FNO3/c21-12-3-1-2-11(8-12)17-16(18(25)10-4-5-10)19(26)20(27)24(17)15-7-6-13(22)9-14(15)23/h1-3,6-10,17,26H,4-5H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]-CCR2-RA-[R] from human TEV protease site linked CCR1 expressed in human U20S cell membranes co-expressing Gal4-VP16 transcriptio...				J Med Chem 61: 9146-9161 (2018) Article DOI: 10.1021/acs.jmedchem.8b00605 BindingDB Entry DOI: 10.7270/Q2222Z5H
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50518092 (CHEMBL4439854) Show SMILES OC1=C(C(N(C1=O)c1ccc(Br)cc1F)c1cccc(Br)c1)C(=O)C1CC1 |t:1| Show InChI InChI=1S/C20H14Br2FNO3/c21-12-3-1-2-11(8-12)17-16(18(25)10-4-5-10)19(26)20(27)24(17)15-7-6-13(22)9-14(15)23/h1-3,6-10,17,26H,4-5H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Antagonist activity at human TEV protease site linked CCR1 expressed in human U20S cell membranes co-expressing Gal4-VP16 transcription factor assess...				J Med Chem 61: 9146-9161 (2018) Article DOI: 10.1021/acs.jmedchem.8b00605 BindingDB Entry DOI: 10.7270/Q2222Z5H
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50518092 (CHEMBL4439854) Show SMILES OC1=C(C(N(C1=O)c1ccc(Br)cc1F)c1cccc(Br)c1)C(=O)C1CC1 |t:1| Show InChI InChI=1S/C20H14Br2FNO3/c21-12-3-1-2-11(8-12)17-16(18(25)10-4-5-10)19(26)20(27)24(17)15-7-6-13(22)9-14(15)23/h1-3,6-10,17,26H,4-5H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Antagonist activity at human TEV protease site linked CCR1 expressed in human U20S cell membranes co-expressing Gal4-VP16 transcription factor assess...				J Med Chem 61: 9146-9161 (2018) Article DOI: 10.1021/acs.jmedchem.8b00605 BindingDB Entry DOI: 10.7270/Q2222Z5H
					More data for this Ligand-Target Pair