Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM140227'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM140227 (US8906911, 36) Show SMILES CO[C@@H]1COCC[C@@H]1N[C@@H]1C[C@H]2CCC[C@]2(C1)C(=O)N1C[C@@H]2C[C@H]1CN2c1cc(ccc1C(F)(F)F)C#N |r| Show InChI InChI=1S/C28H35F3N4O3/c1-37-25-16-38-8-6-23(25)33-19-10-18-3-2-7-27(18,12-19)26(36)35-15-20-11-21(35)14-34(20)24-9-17(13-32)4-5-22(24)28(29,30)31/h4-5,9,18-21,23,25,33H,2-3,6-8,10-12,14-16H2,1H3/t18-,19-,20+,21+,23+,25-,27-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.06E+3	-31.7	305	n/a	n/a	n/a	n/a	7.4	4
AbbVie Inc. US Patent					Assay Description Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha±16 coupling protein. All compounds were dissolved in DMSO a...				US Patent US8906911 (2014) BindingDB Entry DOI: 10.7270/Q2BV7FBV
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