BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50191820'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM50191820
PNG
((2S)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-3-...)
Show SMILES CC(C)[C@H](CCN1CCC2(CC1)C=Cc1ccccc21)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F |c:13|
Show InChI InChI=1S/C29H32F6N2O/c1-19(2)24(8-12-37-13-10-27(11-14-37)9-7-21-5-3-4-6-25(21)27)26(38)36-18-20-15-22(28(30,31)32)17-23(16-20)29(33,34)35/h3-7,9,15-17,19,24H,8,10-14,18H2,1-2H3,(H,36,38)/t24-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 47n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]MCP-1 from human CCR2b expressed in human monocyte cells


Bioorg Med Chem Lett 16: 4715-22 (2006)


Article DOI: 10.1016/j.bmcl.2006.07.011
BindingDB Entry DOI: 10.7270/Q2JD4WDC
More data for this
Ligand-Target Pair
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM50191820
PNG
((2S)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-3-...)
Show SMILES CC(C)[C@H](CCN1CCC2(CC1)C=Cc1ccccc21)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F |c:13|
Show InChI InChI=1S/C29H32F6N2O/c1-19(2)24(8-12-37-13-10-27(11-14-37)9-7-21-5-3-4-6-25(21)27)26(38)36-18-20-15-22(28(30,31)32)17-23(16-20)29(33,34)35/h3-7,9,15-17,19,24H,8,10-14,18H2,1-2H3,(H,36,38)/t24-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 204n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]MCP-1 from human CCR2b expressed in CHO cells


Bioorg Med Chem Lett 16: 4715-22 (2006)


Article DOI: 10.1016/j.bmcl.2006.07.011
BindingDB Entry DOI: 10.7270/Q2JD4WDC
More data for this
Ligand-Target Pair