Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50359134'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359134 (CHEMBL1922818) Show SMILES NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)\C=C\c1ccc(cc1)C(F)(F)F |(25.53,-23.99,;26.87,-24.76,;28.2,-23.99,;26.86,-26.3,;25.52,-27.07,;25.52,-28.61,;24.18,-29.37,;24.18,-30.9,;25.51,-31.68,;26.85,-30.91,;26.85,-29.37,;25.51,-33.22,;24.26,-34.13,;24.74,-35.59,;26.28,-35.58,;27.31,-36.72,;28.81,-36.4,;29.28,-34.93,;28.25,-33.8,;26.75,-34.12,;28.19,-27.07,;28.18,-28.62,;29.5,-29.39,;30.84,-28.63,;30.85,-27.09,;29.52,-26.31,;32.17,-29.41,;32.16,-30.95,;33.51,-28.65,;34.84,-29.43,;36.18,-28.67,;37.5,-29.45,;38.84,-28.69,;38.85,-27.15,;37.51,-26.37,;36.18,-27.13,;40.19,-26.39,;41.52,-27.16,;40.19,-24.85,;41.51,-25.6,)| Show InChI InChI=1S/C31H35F3N4O2/c32-31(33,34)23-10-5-20(6-11-23)7-14-28(39)38-17-15-22(16-18-38)29(30(35)40)37-24-12-8-21(9-13-24)26-19-36-27-4-2-1-3-25(26)27/h1-7,10-11,14,19,21-22,24,29,36-37H,8-9,12-13,15-18H2,(H2,35,40)/b14-7+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica NV US Patent					Assay Description MCP-1 Receptor Binding Assay in THP-1 Cells Human monocytic cell line THP-1 cells were obtained from American Type Culture Collection (Manassas, Va.,...				US Patent US8921559 (2014) BindingDB Entry DOI: 10.7270/Q270804M
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50359134 (CHEMBL1922818) Show SMILES NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)\C=C\c1ccc(cc1)C(F)(F)F |(25.53,-23.99,;26.87,-24.76,;28.2,-23.99,;26.86,-26.3,;25.52,-27.07,;25.52,-28.61,;24.18,-29.37,;24.18,-30.9,;25.51,-31.68,;26.85,-30.91,;26.85,-29.37,;25.51,-33.22,;24.26,-34.13,;24.74,-35.59,;26.28,-35.58,;27.31,-36.72,;28.81,-36.4,;29.28,-34.93,;28.25,-33.8,;26.75,-34.12,;28.19,-27.07,;28.18,-28.62,;29.5,-29.39,;30.84,-28.63,;30.85,-27.09,;29.52,-26.31,;32.17,-29.41,;32.16,-30.95,;33.51,-28.65,;34.84,-29.43,;36.18,-28.67,;37.5,-29.45,;38.84,-28.69,;38.85,-27.15,;37.51,-26.37,;36.18,-27.13,;40.19,-26.39,;41.52,-27.16,;40.19,-24.85,;41.51,-25.6,)| Show InChI InChI=1S/C31H35F3N4O2/c32-31(33,34)23-10-5-20(6-11-23)7-14-28(39)38-17-15-22(16-18-38)29(30(35)40)37-24-12-8-21(9-13-24)26-19-36-27-4-2-1-3-25(26)27/h1-7,10-11,14,19,21-22,24,29,36-37H,8-9,12-13,15-18H2,(H2,35,40)/b14-7+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human CCR2				Bioorg Med Chem Lett 21: 7496-501 (2011) Article DOI: 10.1016/j.bmcl.2011.09.113 BindingDB Entry DOI: 10.7270/Q22J6C9M
					More data for this Ligand-Target Pair