Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 3' and Ligand = 'BDBM50225349'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50225349 (CHEMBL409830 | N-(1-((6-fluoronaphthalen-2-yl)meth...) Show SMILES Fc1ccc2cc(CN3CCC(CC3)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 Show InChI InChI=1S/C29H27FN2O/c30-25-13-12-23-18-21(10-11-24(23)19-25)20-32-16-14-26(15-17-32)31-29(33)28-9-5-4-8-27(28)22-6-2-1-3-7-22/h1-13,18-19,26H,14-17,20H2,(H,31,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Antagonist activity at CCR3 expressed in B300-19 cells assessed as inhibition of eotaxin-induced calcium influx				Bioorg Med Chem 16: 144-56 (2008) Article DOI: 10.1016/j.bmc.2007.10.003 BindingDB Entry DOI: 10.7270/Q2445NBG
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50225349 (CHEMBL409830 | N-(1-((6-fluoronaphthalen-2-yl)meth...) Show SMILES Fc1ccc2cc(CN3CCC(CC3)NC(=O)c3ccccc3-c3ccccc3)ccc2c1 Show InChI InChI=1S/C29H27FN2O/c30-25-13-12-23-18-21(10-11-24(23)19-25)20-32-16-14-26(15-17-32)31-29(33)28-9-5-4-8-27(28)22-6-2-1-3-7-22/h1-13,18-19,26H,14-17,20H2,(H,31,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR3 expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium flux				Bioorg Med Chem 17: 5989-6002 (2009) Article DOI: 10.1016/j.bmc.2009.06.066 BindingDB Entry DOI: 10.7270/Q2WD40NV
					More data for this Ligand-Target Pair