BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 3' and Ligand = 'BDBM50297192'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))		BDBM50297192
PNG
(CHEMBL560135 | N-{(3R)-1-[(6-Fluoro-2-naphthyl)met...)
Show SMILES Fc1ccc2cc(CN3CC[C@H](C3)NC(=O)C=C3CCC(CC3)Oc3ccccc3)ccc2c1 |r|
Show InChI InChI=1S/C29H31FN2O2/c30-25-11-10-23-16-22(6-9-24(23)18-25)19-32-15-14-26(20-32)31-29(33)17-21-7-12-28(13-8-21)34-27-4-2-1-3-5-27/h1-6,9-11,16-18,26,28H,7-8,12-15,19-20H2,(H,31,33)/b21-17-/t26-,28?/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 210n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human CCR3 expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium flux

Bioorg Med Chem 17: 5989-6002 (2009)


Article DOI: 10.1016/j.bmc.2009.06.066
BindingDB Entry DOI: 10.7270/Q2WD40NV
More data for this
Ligand-Target Pair