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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 4' and Ligand = 'BDBM50260893'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 4


(Homo sapiens (Human))		BDBM50260893
PNG
(CHEMBL4096860)
Show SMILES CCNc1nc(NS(=O)(=O)c2cccc(Cl)c2Cl)c2c(OC)nn(C)c2n1
Show InChI InChI=1S/C15H16Cl2N6O3S/c1-4-18-15-19-12(10-13(20-15)23(2)21-14(10)26-3)22-27(24,25)9-7-5-6-8(16)11(9)17/h5-7H,4H2,1-3H3,(H2,18,19,20,22)
UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 251n/an/an/an/an/an/a



Department of Medicinal Chemistry, Respiratory TAU, GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom. Electronic address: afjal.h.miah@gs

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay

Bioorg Med Chem 25: 5327-5340 (2017)


Article DOI: 10.1016/j.bmc.2017.07.052
BindingDB Entry DOI: 10.7270/Q2X350X1
More data for this
Ligand-Target Pair