Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 2' and Ligand = 'BDBM150967'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM150967 (US8981106, 156) Show SMILES OB(O)c1ccccc1CSc1ccc(cn1)C(=O)N(CC1CCCCN1)c1ccc(F)cc1 Show InChI InChI=1S/C25H27BFN3O3S/c27-20-9-11-22(12-10-20)30(16-21-6-3-4-14-28-21)25(31)18-8-13-24(29-15-18)34-17-19-5-1-2-7-23(19)26(32)33/h1-2,5,7-13,15,21,28,32-33H,3-4,6,14,16-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntrix Biosystems Curated by ChEMBL					Assay Description Antagonist activity at CXCR2 in human PMNs assessed as inhibition of CXCL1-induced intracellular Ca2+ release by fluorescence based calcium flux assa...				J Med Chem 57: 8378-97 (2014) Article DOI: 10.1021/jm500827t BindingDB Entry DOI: 10.7270/Q2FX7C22
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM150967 (US8981106, 156) Show SMILES OB(O)c1ccccc1CSc1ccc(cn1)C(=O)N(CC1CCCCN1)c1ccc(F)cc1 Show InChI InChI=1S/C25H27BFN3O3S/c27-20-9-11-22(12-10-20)30(16-21-6-3-4-14-28-21)25(31)18-8-13-24(29-15-18)34-17-19-5-1-2-7-23(19)26(32)33/h1-2,5,7-13,15,21,28,32-33H,3-4,6,14,16-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	37
Syntrix Biosystems, Inc. US Patent					Assay Description An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release. Briefly, human neutrophils were suspended in HBSS- (without Ca2+...				US Patent US8981106 (2015) BindingDB Entry DOI: 10.7270/Q2WW7GC1
					More data for this Ligand-Target Pair