Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'C5a anaphylatoxin chemotactic receptor 1' and Ligand = 'BDBM50305740'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human))	BDBM50305740 (CHEMBL603858 | N-(2-(indoline-1-carbonyl)phenyl)-N...) Show SMILES CN(c1ccccc1C(=O)N1CCc2ccccc12)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C23H22N2O3S/c1-17-11-13-19(14-12-17)29(27,28)24(2)22-10-6-4-8-20(22)23(26)25-16-15-18-7-3-5-9-21(18)25/h3-14H,15-16H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as inhibition of anaphylatoxin C5a-induced intra...				Bioorg Med Chem Lett 20: 662-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.058 BindingDB Entry DOI: 10.7270/Q2B8586C
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human))	BDBM50305740 (CHEMBL603858 | N-(2-(indoline-1-carbonyl)phenyl)-N...) Show SMILES CN(c1ccccc1C(=O)N1CCc2ccccc12)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C23H22N2O3S/c1-17-11-13-19(14-12-17)29(27,28)24(2)22-10-6-4-8-20(22)23(26)25-16-15-18-7-3-5-9-21(18)25/h3-14H,15-16H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [125I]human anaphylatoxin C5a from human C5a receptor expressed in CHO cells co-expressed with Galpha16 after 1 hr				Bioorg Med Chem Lett 20: 662-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.058 BindingDB Entry DOI: 10.7270/Q2B8586C
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human))	BDBM50305740 (CHEMBL603858 | N-(2-(indoline-1-carbonyl)phenyl)-N...) Show SMILES CN(c1ccccc1C(=O)N1CCc2ccccc12)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C23H22N2O3S/c1-17-11-13-19(14-12-17)29(27,28)24(2)22-10-6-4-8-20(22)23(26)25-16-15-18-7-3-5-9-21(18)25/h3-14H,15-16H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as effect on anaphylatoxin C5a-induced intracellula...				Bioorg Med Chem Lett 20: 662-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.058 BindingDB Entry DOI: 10.7270/Q2B8586C
					More data for this Ligand-Target Pair