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Found 1 hit Enz. Inhib. hit(s) with Target = 'CAAX prenyl protease 2' and Ligand = 'BDBM50500091'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
CAAX prenyl protease 2


(Homo sapiens (Human))		BDBM50500091
PNG
(CHEMBL3740563)
Show SMILES Cc1ccc(cc1)C(Nc1ccc(cc1)C(O)=O)c1ccc2cccnc2c1O
Show InChI InChI=1S/C24H20N2O3/c1-15-4-6-17(7-5-15)21(26-19-11-8-18(9-12-19)24(28)29)20-13-10-16-3-2-14-25-22(16)23(20)27/h2-14,21,26-27H,1H3,(H,28,29)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.10E+3n/an/an/an/an/an/a



New York University Abu Dhabi

Curated by ChEMBL


Assay Description
Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua...

Bioorg Med Chem 24: 160-78 (2016)


Article DOI: 10.1016/j.bmc.2015.11.043
BindingDB Entry DOI: 10.7270/Q2NS0XXQ
More data for this
Ligand-Target Pair