Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM50525156![]() (CHEMBL4476248) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Australia Curated by ChEMBL | Assay Description Inhibition of CDK7/cyclinH/MAT1 (unknown origin) using RBER-IRStide as substrate incubated for 120 mins in presence of ATP by ADP-Glo kinase assay | ACS Med Chem Lett 10: 786-791 (2019) Article DOI: 10.1021/acsmedchemlett.9b00029 BindingDB Entry DOI: 10.7270/Q2X06BGP | |||||||||||
More data for this Ligand-Target Pair |