Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7' and Ligand = 'BDBM50525157'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM50525157 (CHEMBL4460155) Show SMILES COc1cccc(Nc2ncc3CCCCc3n2)c1 Show InChI InChI=1S/C15H17N3O/c1-19-13-7-4-6-12(9-13)17-15-16-10-11-5-2-3-8-14(11)18-15/h4,6-7,9-10H,2-3,5,8H2,1H3,(H,16,17,18)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Australia Curated by ChEMBL					Assay Description Inhibition of CDK7/cyclinH/MAT1 (unknown origin) using RBER-IRStide as substrate incubated for 120 mins in presence of ATP by ADP-Glo kinase assay				ACS Med Chem Lett 10: 786-791 (2019) Article DOI: 10.1021/acsmedchemlett.9b00029 BindingDB Entry DOI: 10.7270/Q2X06BGP
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