Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'COP9 signalosome complex subunit 5' and Ligand = 'BDBM50264426'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
COP9 signalosome complex subunit 5 (Homo sapiens (Human))	BDBM50264426 (CHEMBL4095913) Show SMILES O=C(NCc1ccco1)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCc3ccco3)cccc2c1 Show InChI InChI=1S/C30H22N4O4S2/c35-29(33-17-23-7-3-11-37-23)21-13-19-5-1-9-25(27(19)31-15-21)39-40-26-10-2-6-20-14-22(16-32-28(20)26)30(36)34-18-24-8-4-12-38-24/h1-16H,17-18H2,(H,33,35)(H,34,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assay				J Med Chem 60: 1343-1361 (2017) Article DOI: 10.1021/acs.jmedchem.6b01379 BindingDB Entry DOI: 10.7270/Q22F7QX5
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