Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Calcitonin gene-related peptide type 1 receptor' and Ligand = 'BDBM50255005'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50255005 ((R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imida...) Show SMILES CN1C(=O)NC(=O)[C@]11Cc2ccc(NC(=O)CN3C(=O)C4(CCOCC4)c4ccccc34)cc2C1 |r| Show InChI InChI=1S/C26H26N4O5/c1-29-24(34)28-22(32)26(29)13-16-6-7-18(12-17(16)14-26)27-21(31)15-30-20-5-3-2-4-19(20)25(23(30)33)8-10-35-11-9-25/h2-7,12H,8-11,13-15H2,1H3,(H,27,31)(H,28,32,34)/t26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co Curated by ChEMBL					Assay Description Displacement of [125I]hCGRP from human CGRP receptor expressed in HEK293 cells coexpressing RAMP1				Bioorg Med Chem Lett 19: 214-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.106 BindingDB Entry DOI: 10.7270/Q21C1XSK
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50255005 ((R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imida...) Show SMILES CN1C(=O)NC(=O)[C@]11Cc2ccc(NC(=O)CN3C(=O)C4(CCOCC4)c4ccccc34)cc2C1 |r| Show InChI InChI=1S/C26H26N4O5/c1-29-24(34)28-22(32)26(29)13-16-6-7-18(12-17(16)14-26)27-21(31)15-30-20-5-3-2-4-19(20)25(23(30)33)8-10-35-11-9-25/h2-7,12H,8-11,13-15H2,1H3,(H,27,31)(H,28,32,34)/t26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co Curated by ChEMBL					Assay Description Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP production				Bioorg Med Chem Lett 19: 214-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.106 BindingDB Entry DOI: 10.7270/Q21C1XSK
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50255005 ((R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imida...) Show SMILES CN1C(=O)NC(=O)[C@]11Cc2ccc(NC(=O)CN3C(=O)C4(CCOCC4)c4ccccc34)cc2C1 |r| Show InChI InChI=1S/C26H26N4O5/c1-29-24(34)28-22(32)26(29)13-16-6-7-18(12-17(16)14-26)27-21(31)15-30-20-5-3-2-4-19(20)25(23(30)33)8-10-35-11-9-25/h2-7,12H,8-11,13-15H2,1H3,(H,27,31)(H,28,32,34)/t26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co Curated by ChEMBL					Assay Description Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP production in p...				Bioorg Med Chem Lett 19: 214-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.106 BindingDB Entry DOI: 10.7270/Q21C1XSK
					More data for this Ligand-Target Pair