Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calcium/calmodulin-dependent protein kinase kinase 2 (Homo sapiens (Human)) | BDBM50572896![]() (CHEMBL4862562) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to control | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02274 BindingDB Entry DOI: 10.7270/Q2MG7T9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium/calmodulin-dependent protein kinase kinase 2 (Homo sapiens (Human)) | BDBM50572896![]() (CHEMBL4862562) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02274 BindingDB Entry DOI: 10.7270/Q2MG7T9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium/calmodulin-dependent protein kinase kinase 2 (Homo sapiens (Human)) | BDBM50572896![]() (CHEMBL4862562) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CAMKK2 in human LNCaP C4-2 cells assessed as reduction AMPK phosphorylation at Thr172 incubated for 24 hrs by Western blot analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02274 BindingDB Entry DOI: 10.7270/Q2MG7T9N | |||||||||||
More data for this Ligand-Target Pair |