Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase type II subunit gamma' and Ligand = 'BDBM458842'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type II subunit gamma (Homo sapiens (Human))	BDBM458842 (US10759792, Compound I-11 | US11325908, Compound I...) Show SMILES Cc1ccc2c(c1)[nH]c1nccc(-c3cccc(NCCN)c3)c21 Show InChI InChI=1S/C20H20N4/c1-13-5-6-17-18(11-13)24-20-19(17)16(7-9-23-20)14-3-2-4-15(12-14)22-10-8-21/h2-7,9,11-12,22H,8,10,21H2,1H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZC863Z
					More data for this Ligand-Target Pair