Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Calcium release-activated calcium channel protein 1' and Ligand = 'BDBM141404'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium release-activated calcium channel protein 1 (Homo sapiens (Human))	BDBM141404 (US10668051, Compound Example 35 | US8921364, 35) Show SMILES Fc1cc(NC(=O)c2ccncc2)ccc1-n1nc(cc1C1CC1)C1CC1 Show InChI InChI=1S/C21H19FN4O/c22-17-11-16(24-21(27)15-7-9-23-10-8-15)5-6-19(17)26-20(14-3-4-14)12-18(25-26)13-1-2-13/h5-14H,1-4H2,(H,24,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
RHIZEN PHARMACEUTICALS SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat #T9033) induced endoplasmic calcium release in Jurkat cells, (see Yasur...				US Patent US10668051 (2020) BindingDB Entry DOI: 10.7270/Q2V40Z7G
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