BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Calmodulin-domain protein kinase 1' and Ligand = 'BDBM50250009'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calmodulin-domain protein kinase 1


(Toxoplasma gondii)		BDBM50250009
PNG
(CHEMBL4096137 | US11208411, Compound FUR)
Show SMILES Nc1ncnc2n(CC3CCNCC3)nc(Cc3cccc(Cl)c3)c12
Show InChI InChI=1S/C18H21ClN6/c19-14-3-1-2-13(8-14)9-15-16-17(20)22-11-23-18(16)25(24-15)10-12-4-6-21-7-5-12/h1-3,8,11-12,21H,4-7,9-10H2,(H2,20,22,23)
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 15n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His-tagged full length Toxoplasma gondii CDPK1 expressed in Escherichia coli BL21 (DE3) using syntide-2 as substrate pre-inc...

J Med Chem 60: 9976-9989 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01192
BindingDB Entry DOI: 10.7270/Q21G0PP0
More data for this
Ligand-Target Pair