Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 1' and Ligand = 'BDBM111130'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM111130 (US9682940, 23) Show SMILES NS(=O)(=O)N1CCC(CC1)c1n[nH]c2ccc(cc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H24Cl2N4O2S/c26-20-6-1-16(2-7-20)24(17-3-8-21(27)9-4-17)19-5-10-23-22(15-19)25(30-29-23)18-11-13-31(14-12-18)34(28,32)33/h1-10,15,18,24H,11-14H2,(H,29,30)(H2,28,32,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.15E+3	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description CB1 and CB2 receptors are Gi-coupled GPCR. Activation of CB1 and CB2 receptors results in a decrease in cAMP production. An inverse agonist of the CB...				US Patent US9682940 (2017) BindingDB Entry DOI: 10.7270/Q2M61HD7
					More data for this Ligand-Target Pair