Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cannabinoid receptor 1' and Ligand = 'BDBM113303'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM113303 (US9682940, 43) Show SMILES NC(=O)CCC(=O)N1CCC(CC1)c1n[nH]c2ccc(cc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C29H28Cl2N4O2/c30-22-6-1-18(2-7-22)28(19-3-8-23(31)9-4-19)21-5-10-25-24(17-21)29(34-33-25)20-13-15-35(16-14-20)27(37)12-11-26(32)36/h1-10,17,20,28H,11-16H2,(H2,32,36)(H,33,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	169	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description CB1 and CB2 receptors are Gi-coupled GPCR. Activation of CB1 and CB2 receptors results in a decrease in cAMP production. An inverse agonist of the CB...				US Patent US9682940 (2017) BindingDB Entry DOI: 10.7270/Q2M61HD7
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