Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50329833 (5-[(1H-Benzimidazol-2-ylsulfanyl)acetyl]-2-chlorob...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a |
Institute of Biotechnology Curated by ChEMBL | Assay Description Binding affinity to human recombinant carbonic anhydrase 1 by isothermal titration calorimetry assay | Bioorg Med Chem 18: 7357-64 (2010) Article DOI: 10.1016/j.bmc.2010.09.016 BindingDB Entry DOI: 10.7270/Q21V5F6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50329833 (5-[(1H-Benzimidazol-2-ylsulfanyl)acetyl]-2-chlorob...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a |
Institute of Biotechnology Curated by ChEMBL | Assay Description Binding affinity to human recombinant carbonic anhydrase 1 by thermal shift assay | Bioorg Med Chem 18: 7357-64 (2010) Article DOI: 10.1016/j.bmc.2010.09.016 BindingDB Entry DOI: 10.7270/Q21V5F6H | |||||||||||
More data for this Ligand-Target Pair |