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Found 1 hit Enz. Inhib. hit(s) with Target = 'Carbonic anhydrase 2' and Ligand = 'BDBM50504749'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))		BDBM50504749
PNG
(CHEMBL4461308)
Show SMILES Nc1nc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)N\N=C\c1ccc(cc1)N1CCCCC1
Show InChI InChI=1S/C21H24N8O3S/c22-21-25-19(27-29(21)17-8-10-18(11-9-17)33(23,31)32)20(30)26-24-14-15-4-6-16(7-5-15)28-12-2-1-3-13-28/h4-11,14H,1-3,12-13H2,(H,26,30)(H2,22,25,27)(H2,23,31,32)/b24-14+
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 95n/an/an/an/an/an/an/an/a



Egyptian Russian University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase-2 incubated for 15 mins by stopped flow CO2 hydrase assay

Eur J Med Chem 185: (2020)


Article DOI: 10.1016/j.ejmech.2019.111843
BindingDB Entry DOI: 10.7270/Q2WW7N05
More data for this
Ligand-Target Pair