Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Casein kinase I isoform delta' and Ligand = 'BDBM302774'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM302774 (N5-(3- Chloro-4-cyanophenyl)- 2-(3-chlorophenyl)-7...) Show SMILES NC(=O)c1c2CN(CC(CO)n2nc1-c1cccc(Cl)c1)C(=O)Nc1ccc(C#N)c(Cl)c1 |$;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;$| Show InChI InChI=1S/C22H18Cl2N6O3/c23-14-3-1-2-12(6-14)20-19(21(26)32)18-10-29(9-16(11-31)30(18)28-20)22(33)27-15-5-4-13(8-25)17(24)7-15/h1-7,16,31H,9-11H2,(H2,26,32)(H,27,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
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