Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM50420563![]() (CHEMBL2087023) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Curated by ChEMBL | Assay Description Inhibition of GST-tagged human CK2alpha (1 to 391 residues) using CK2tide as substrate incubated for 1 hr by off-chip mobility shift assay | Bioorg Med Chem 24: 1136-41 (2016) Article DOI: 10.1016/j.bmc.2016.01.043 BindingDB Entry DOI: 10.7270/Q2BK1F7G | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM50420563![]() (CHEMBL2087023) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Beijing University of Technology Curated by ChEMBL | Assay Description Inhibition of human CK2alpha (2 to 391 residues) using [33P]-ATP by scintillation counting based radioactive filter binding assay | Bioorg Med Chem Lett 26: 3594-7 (2016) Article DOI: 10.1016/j.bmcl.2016.06.013 BindingDB Entry DOI: 10.7270/Q2V40X4Q | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM50420563![]() (CHEMBL2087023) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Curated by ChEMBL | Assay Description Competitive inhibition of GST fused human CK2alpha expressed in Escherichia coli BL21 after 10 mins in presence of ATP | J Med Chem 55: 2899-903 (2012) Article DOI: 10.1021/jm2015167 BindingDB Entry DOI: 10.7270/Q2445NRV | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |