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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cathepsin D' and Ligand = 'BDBM50006843'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cathepsin D


(Bos taurus)		BDBM50006843
PNG
(CHEMBL314066 | N-[(2-Amino-thiazol-4-yl)-(1-cycloh...)
Show SMILES CC(C)C[C@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)C(NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCOCC1)c1csc(N)n1
Show InChI InChI=1S/C32H50N6O7S2/c1-21(2)17-27(39)29(40)24(18-22-9-5-3-6-10-22)34-31(42)28(26-20-46-32(33)35-26)36-30(41)25(19-23-11-7-4-8-12-23)37-47(43,44)38-13-15-45-16-14-38/h4,7-8,11-12,20-22,24-25,27-29,37,39-40H,3,5-6,9-10,13-19H2,1-2H3,(H2,33,35)(H,34,42)(H,36,41)/t24-,25-,27-,28?,29+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 86n/an/an/an/an/an/a



Parke-Davis Pharmaceutical Research Division of Warner-Lambert Co.

Curated by ChEMBL


Assay Description
Inhibition of Bovine Cathepsin D

J Med Chem 35: 2562-72 (1992)


BindingDB Entry DOI: 10.7270/Q2ZK5H8V
More data for this
Ligand-Target Pair