Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cathepsin K' and Ligand = 'BDBM138146'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM138146 (US8877967, 13) Show SMILES NC(=S)NN=C(c1ccc(F)cc1)c1cccc(c1)C(=O)c1ccc(F)cc1 |w:4.3| Show InChI InChI=1S/C21H15F2N3OS/c22-17-8-4-13(5-9-17)19(25-26-21(24)28)15-2-1-3-16(12-15)20(27)14-6-10-18(23)11-7-14/h1-12H,(H3,24,26,28)/b25-19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	3.5	25
OXiGENE, Inc.; Baylor University US Patent					Assay Description Recombinant human procathepsin K was obtained from Enzo Life Sciences. Activation of the proenzyme was performed in 32.5 mM sodium acetate pH 3.5, ED...				US Patent US8877967 (2014) BindingDB Entry DOI: 10.7270/Q25H7F0C
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