Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cathepsin K' and Ligand = 'BDBM139506'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM139506 (US8889708, 4) Show SMILES CN1Cc2cc(ccc2C1=O)-c1ccc(C[C@H](NC(=O)C23CCC(CC2)CN3)C#N)cc1 |r| Show InChI InChI=1S/C26H28N4O2/c1-30-16-21-13-20(6-7-23(21)24(30)31)19-4-2-17(3-5-19)12-22(14-27)29-25(32)26-10-8-18(9-11-26)15-28-26/h2-7,13,18,22,28H,8-12,15-16H2,1H3,(H,29,32)/t18?,22-,26?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...				US Patent US8889708 (2014) BindingDB Entry DOI: 10.7270/Q2JM28BB
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