Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cathepsin K' and Ligand = 'BDBM139532'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM139532 (US8889708, 31) Show SMILES NC(=O)c1cc(cs1)-c1ccc(C[C@H](NC(=O)C23CCC(CC2)CN3)C#N)c(F)c1 |r| Show InChI InChI=1S/C22H23FN4O2S/c23-18-8-14(16-9-19(20(25)28)30-12-16)1-2-15(18)7-17(10-24)27-21(29)22-5-3-13(4-6-22)11-26-22/h1-2,8-9,12-13,17,26H,3-7,11H2,(H2,25,28)(H,27,29)/t13?,17-,22?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...				US Patent US8889708 (2014) BindingDB Entry DOI: 10.7270/Q2JM28BB
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