Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cell division protein FtsZ' and Ligand = 'BDBM50085995'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Bacillus subtilis)	BDBM50085995 (CHEMBL3425682) Show SMILES CN(C)CCNc1nc(NCc2ccc(Cl)cc2)nc2ccc(C)cc12 Show InChI InChI=1S/C20H24ClN5/c1-14-4-9-18-17(12-14)19(22-10-11-26(2)3)25-20(24-18)23-13-15-5-7-16(21)8-6-15/h4-9,12H,10-11,13H2,1-3H3,(H2,22,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
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