Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cell division protein FtsZ' and Ligand = 'BDBM50086048'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Bacillus subtilis)	BDBM50086048 (CHEMBL3425616) Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(cc2)C(F)(F)F)nc2ccc(C)cc12 Show InChI InChI=1S/C22H23F3N4/c1-15-4-10-19-18(14-15)21(26-12-13-29(2)3)28-20(27-19)11-7-16-5-8-17(9-6-16)22(23,24)25/h4-11,14H,12-13H2,1-3H3,(H,26,27,28)/b11-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Bacillus subtilis FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair