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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cell division protein FtsZ' and Ligand = 'BDBM50392993'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cell division protein FtsZ


(Bacillus subtilis)
BDBM50392993
PNG
(TOTAROL)
Show SMILES CC(C)c1c(O)ccc2c1CC[C@H]1C(C)(C)CCC[C@]21C |r|
Show InChI InChI=1S/C20H30O/c1-13(2)18-14-7-10-17-19(3,4)11-6-12-20(17,5)15(14)8-9-16(18)21/h8-9,13,17,21H,6-7,10-12H2,1-5H3/t17-,20+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.40E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Bacillus subtilis FtsZ GTPase activity by enzyme-coupled assay


ACS Med Chem Lett 3: 818-822 (2012)


Article DOI: 10.1021/ml3001775
BindingDB Entry DOI: 10.7270/Q2XG9S7W
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Mycobacterium tuberculosis)
BDBM50392993
PNG
(TOTAROL)
Show SMILES CC(C)c1c(O)ccc2c1CC[C@H]1C(C)(C)CCC[C@]21C |r|
Show InChI InChI=1S/C20H30O/c1-13(2)18-14-7-10-17-19(3,4)11-6-12-20(17,5)15(14)8-9-16(18)21/h8-9,13,17,21H,6-7,10-12H2,1-5H3/t17-,20+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.10E+4n/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Binding affinity to Mycobacterium tuberculosis FtsZ


Eur J Med Chem 95: 1-15 (2015)


Article DOI: 10.1016/j.ejmech.2015.03.026
BindingDB Entry DOI: 10.7270/Q2S75J14
More data for this
Ligand-Target Pair