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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Cell division protein FtsZ' and Ligand = 'BDBM81334'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cell division protein FtsZ


(Aquifex aeolicus)
BDBM81334
PNG
(MeGTP (1b))
Show SMILES Cc1nc2c(nc(N)[nH]c2=O)n1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)C(O)C1O |r|
Show InChI InChI=1S/C11H18N5O14P3/c1-3-13-5-8(14-11(12)15-9(5)19)16(3)10-7(18)6(17)4(28-10)2-27-32(23,24)30-33(25,26)29-31(20,21)22/h4,6-7,10,17-18H,2H2,1H3,(H,23,24)(H,25,26)(H2,20,21,22)(H3,12,14,15,19)/p-3/t4-,6?,7?,10-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.40E+4n/an/an/an/a7.5n/a



University of Amsterdam



Assay Description
The binding affinities to FtsZ were determined by a fluorescent competition assay with 2'/3'-O-(N-methyl-anthraniloyl)-guanosine-5'-triph...


Chem Biol 15: 189-99 (2008)


Article DOI: 10.1016/j.chembiol.2007.12.013
BindingDB Entry DOI: 10.7270/Q2P849CR
More data for this
Ligand-Target Pair
Cell division protein FtsZ


(Aquifex aeolicus)
BDBM81334
PNG
(MeGTP (1b))
Show SMILES Cc1nc2c(nc(N)[nH]c2=O)n1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)C(O)C1O |r|
Show InChI InChI=1S/C11H18N5O14P3/c1-3-13-5-8(14-11(12)15-9(5)19)16(3)10-7(18)6(17)4(28-10)2-27-32(23,24)30-33(25,26)29-31(20,21)22/h4,6-7,10,17-18H,2H2,1H3,(H,23,24)(H,25,26)(H2,20,21,22)(H3,12,14,15,19)/p-3/t4-,6?,7?,10-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.20E+4n/an/an/an/a7.5n/a



University of Amsterdam



Assay Description
The binding affinities to FtsZ were determined by a fluorescent coupled assay for phosphate relase. In this GTPase studies, phosphate liberated durin...


Chem Biol 15: 189-99 (2008)


Article DOI: 10.1016/j.chembiol.2007.12.013
BindingDB Entry DOI: 10.7270/Q2P849CR
More data for this
Ligand-Target Pair