Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM388679 (2-((2S,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)pip...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
OncoArendi Therapeutics S.A. US Patent | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | US Patent US10538508 (2020) BindingDB Entry DOI: 10.7270/Q2W37ZQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chitotriosidase-1 (Homo sapiens (Human)) | BDBM388679 (2-((2S,5S)-4-(1-(5-amino-4H-1,2,4-triazol-3-yl)pip...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute | Assay Description An enzymatic assay with recombinant human CHIT1 was used in order to establish inhibitory activity of the compounds (Boot et al., 2001, JBC: 276). Th... | Bioorg Med Chem Lett 19: 1164-7 (2009) BindingDB Entry DOI: 10.7270/Q22N54MD | |||||||||||
More data for this Ligand-Target Pair |