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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chloride anion exchanger' and Ligand = 'BDBM50519172'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chloride anion exchanger


(Mus musculus)		BDBM50519172
PNG
(CHEMBL4562582)
Show SMILES Cc1c(OCc2cc(ccc2F)C(F)(F)F)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C21H16F4O5/c1-10-14-4-6-17(11(2)19(14)30-20(28)15(10)8-18(26)27)29-9-12-7-13(21(23,24)25)3-5-16(12)22/h3-7H,8-9H2,1-2H3,(H,26,27)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair