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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chloride anion exchanger' and Ligand = 'BDBM50519181'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chloride anion exchanger


(Mus musculus)		BDBM50519181
PNG
(CHEMBL4462339)
Show SMILES Cc1c(OCC2CCCC2)ccc2c(C)c(CC(O)=O)c(=O)oc12
Show InChI InChI=1S/C19H22O5/c1-11-14-7-8-16(23-10-13-5-3-4-6-13)12(2)18(14)24-19(22)15(11)9-17(20)21/h7-8,13H,3-6,9-10H2,1-2H3,(H,20,21)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...

J Med Chem 62: 8330-8337 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01192
BindingDB Entry DOI: 10.7270/Q2NG4V1N
More data for this
Ligand-Target Pair