Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chloride anion exchanger' and Ligand = 'BDBM50519197'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chloride anion exchanger (Mus musculus)	BDBM50519197 (CHEMBL1491046) Show SMILES Cc1cc(C)cc(COc2ccc3c(C)c(CC(O)=O)c(=O)oc3c2C)c1 Show InChI InChI=1S/C22H22O5/c1-12-7-13(2)9-16(8-12)11-26-19-6-5-17-14(3)18(10-20(23)24)22(25)27-21(17)15(19)4/h5-9H,10-11H2,1-4H3,(H,23,24)	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of mouse slc26a3 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exch...				J Med Chem 62: 8330-8337 (2019) Article DOI: 10.1021/acs.jmedchem.9b01192 BindingDB Entry DOI: 10.7270/Q2NG4V1N
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