Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholesteryl ester transfer protein (Homo sapiens (Human)) | BDBM50092197![]() (CHEMBL313006 | S-2-(1-(2-ethylbutyl)cyclohexanecar...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research, Inc. Curated by ChEMBL | Assay Description Inhibition of CETP in human plasma measured every 30 mins for 120 mins by fluorescence method | J Med Chem 60: 8466-8481 (2017) Article DOI: 10.1021/acs.jmedchem.7b00900 BindingDB Entry DOI: 10.7270/Q27083WQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholesteryl ester transfer protein (Homo sapiens (Human)) | BDBM50092197![]() (CHEMBL313006 | S-2-(1-(2-ethylbutyl)cyclohexanecar...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of CETP activity was assessed by measuring the rate of [3H]- cholesteryl ester transfer from HDL to apoprotein B-containing lipop... | Bioorg Med Chem Lett 14: 2589-91 (2004) Article DOI: 10.1016/j.bmcl.2004.02.071 BindingDB Entry DOI: 10.7270/Q2VQ324C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholesteryl ester transfer protein (Homo sapiens (Human)) | BDBM50092197![]() (CHEMBL313006 | S-2-(1-(2-ethylbutyl)cyclohexanecar...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro concentration required to inhibit 50% of cholesteryl ester transfer protein mediated cholesteryl ester transfer from HDL to VLDL and LDL in ... | J Med Chem 43: 3566-72 (2000) BindingDB Entry DOI: 10.7270/Q22J6CK6 | |||||||||||
More data for this Ligand-Target Pair |