BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Cholesteryl ester transfer protein' and Ligand = 'BDBM50094514'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094514 (1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal da Bahia Curated by ChEMBL					Assay Description Inhibition of CETP				Bioorg Med Chem 15: 6242-52 (2007) Article DOI: 10.1016/j.bmc.2007.06.021 BindingDB Entry DOI: 10.7270/Q2B857VG
Universidade Federal da Bahia Curated by ChEMBL					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094514 (1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Discovery Research Curated by ChEMBL					Assay Description Inhibition of recombinant human CETP-mediated transfer of [3H]-CE from HDL to LDL				J Med Chem 43: 4575-8 (2001) BindingDB Entry DOI: 10.7270/Q2X0669S
Pharmacia Discovery Research Curated by ChEMBL					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Oryctolagus cuniculus)	BDBM50094514 (1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Zaytoonah Private University of Jordan Curated by ChEMBL					Assay Description Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assay				Eur J Med Chem 45: 1598-617 (2010) Article DOI: 10.1016/j.ejmech.2009.12.070 BindingDB Entry DOI: 10.7270/Q2VQ32VS
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094514 (1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.				J Med Chem 45: 3891-904 (2002) BindingDB Entry DOI: 10.7270/Q2JW8D7P
Pharmacia Curated by ChEMBL					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094514 (1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Discovery Research Curated by ChEMBL					Assay Description Tested for inhibiting CETP-mediated transfer of [3H]-CE from HDL to LDL in vitro under buffered assay conditions in human serum.				J Med Chem 43: 4575-8 (2001) BindingDB Entry DOI: 10.7270/Q2X0669S
Pharmacia Discovery Research Curated by ChEMBL					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094514 (1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Curated by ChEMBL					Assay Description Inhibition of cholesteryl ester transfer protein in presence of human serum				J Med Chem 45: 3891-904 (2002) BindingDB Entry DOI: 10.7270/Q2JW8D7P
Pharmacia Curated by ChEMBL					More data for this Ligand-Target Pair