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Found 1 hit Enz. Inhib. hit(s) with Target = 'Cholinesterase' and Ligand = 'BDBM50456819'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholinesterase


(Equus caballus (Horse))		BDBM50456819
PNG
(CHEMBL4213874)
Show SMILES [Br-].Cc1ccc(C[n+]2ccc(COc3ccc4c(C)cc(=O)oc4c3)cc2)cc1
Show InChI InChI=1S/C24H22NO3/c1-17-3-5-19(6-4-17)15-25-11-9-20(10-12-25)16-27-21-7-8-22-18(2)13-24(26)28-23(22)14-21/h3-14H,15-16H2,1-2H3/q+1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.70n/an/an/an/an/an/a



Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL


Assay Description
Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition measured up to...

Eur J Med Chem 139: 48-59 (2017)


Article DOI: 10.1016/j.ejmech.2017.07.055
BindingDB Entry DOI: 10.7270/Q2GM89X1
More data for this
Ligand-Target Pair