BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cholinesterase' and Ligand = 'BDBM50536298'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholinesterase


(Equus caballus (Horse))		BDBM50536298
PNG
(CHEMBL4551175)
Show SMILES Cc1ccc(cc1C(=O)NCCN1CCOCC1)-c1cn(Cc2ccc(cc2)C#N)nn1
Show InChI InChI=1S/C24H26N6O2/c1-18-2-7-21(14-22(18)24(31)26-8-9-29-10-12-32-13-11-29)23-17-30(28-27-23)16-20-5-3-19(15-25)4-6-20/h2-7,14,17H,8-13,16H2,1H3,(H,26,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.28E+4n/an/an/an/an/an/a



University of Jinan

Curated by ChEMBL


Assay Description
Inhibition of equine serum BuChE preincubated for 6 mins followed by addition of S-butyrylthiocholine iodide by Ellman's method

Bioorg Med Chem Lett 26: 3881-5 (2016)


Article DOI: 10.1016/j.bmcl.2016.07.017
BindingDB Entry DOI: 10.7270/Q2KW5KJZ
More data for this
Ligand-Target Pair