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Found 1 hit Enz. Inhib. hit(s) with Target = 'Chromatin remodeling regulator CECR2' and Ligand = 'BDBM321465'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chromatin remodeling regulator CECR2


(Homo sapiens (Human))		BDBM321465
PNG
(6-but-3-enyl-4-[3-methyl-7-(morpholine-4-carbonyl)...)
Show SMILES Cn1cnc2c(cc(cc12)-c1cn(CCC=C)c(=O)c2[nH]ccc12)C(=O)N1CCOCC1
Show InChI InChI=1S/C24H25N5O3/c1-3-4-7-29-14-19(17-5-6-25-22(17)24(29)31)16-12-18(21-20(13-16)27(2)15-26-21)23(30)28-8-10-32-11-9-28/h3,5-6,12-15,25H,1,4,7-11H2,2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 360n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant His-tagged CECR2 (unknown origin) after 10 mins by TR-FRET assay

J Med Chem 61: 9301-9315 (2018)


Article DOI: 10.1021/acs.jmedchem.8b01225
BindingDB Entry DOI: 10.7270/Q2NV9NH4
More data for this
Ligand-Target Pair