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Found 1 hit Enz. Inhib. hit(s) with Target = 'Chromatin remodeling regulator CECR2' and Ligand = 'BDBM50514875'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chromatin remodeling regulator CECR2


(Homo sapiens (Human))		BDBM50514875
PNG
(CHEMBL4542904)
Show SMILES C[C@H]1CCN(C1)S(=O)(=O)c1cc(NC(=O)Cn2cc(CN(C)C)nn2)ccc1Br |r|
Show InChI InChI=1S/C18H25BrN6O3S/c1-13-6-7-25(9-13)29(27,28)17-8-14(4-5-16(17)19)20-18(26)12-24-11-15(21-22-24)10-23(2)3/h4-5,8,11,13H,6-7,9-10,12H2,1-3H3,(H,20,26)/t13-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 251n/an/an/an/an/an/a



University of Strathclyde

Curated by ChEMBL


Assay Description
Displacement of Alexa Fluor 647-labeled GSK tracer from FLAG-6His-Tev-fused CECR2 (424 to 543 residue) (unknown origin) measured after 15 mins by TR-...

J Med Chem 63: 5212-5241 (2020)


Article DOI: 10.1021/acs.jmedchem.0c00021
BindingDB Entry DOI: 10.7270/Q2RN3C7T
More data for this
Ligand-Target Pair